The Adenosine A(2B) Receptor Drives Osteoclast-Mediated Bone Resorption in Hypoxic Microenvironments

Osteoclast-mediated bone destruction is amplified in the hypoxic synovial microenvironment of rheumatoid arthritis (RA). This increased bone resorption is driven by the hypoxia-inducible transcription factor HIF. We identified hypoxic induction of the HIF-regulated adenosine A(2B) receptor in primar...

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Detalles Bibliográficos
Autor principal: Knowles, Helen J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6628620/
https://www.ncbi.nlm.nih.gov/pubmed/31234425
http://dx.doi.org/10.3390/cells8060624

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6628620/
https://www.ncbi.nlm.nih.gov/pubmed/31234425
http://dx.doi.org/10.3390/cells8060624

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