The role of gelsolin domain 3 in familial amyloidosis (Finnish type)

In the disease familial amyloidosis, Finnish type (FAF), also known as AGel amyloidosis (AGel), the mechanism by which point mutations in the calcium-regulated actin-severing protein gelsolin lead to furin cleavage is not understood in the intact protein. Here, we provide a structural and biochemica...

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Detalles Bibliográficos
Autores principales: Zorgati, Habiba, Larsson, Mårten, Ren, Weitong, Sim, Adelene Y. L., Gettemans, Jan, Grimes, Jonathan M., Li, Wenfei, Robinson, Robert C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2019
Materias:
Biological Sciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6628662/
https://www.ncbi.nlm.nih.gov/pubmed/31243148
http://dx.doi.org/10.1073/pnas.1902189116

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6628662/
https://www.ncbi.nlm.nih.gov/pubmed/31243148
http://dx.doi.org/10.1073/pnas.1902189116

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