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Rational design and implementation of a cucurbit[8]uril-based indicator-displacement assay for application in blood serum

In this study, we report the first supramolecular indicator-displacement assay (IDA) based on cucurbit[n]uril (CBn) hosts that is operational in blood serum. Rational design principles for host–guest chemosensing in competitively binding media were derived through detailed mathematical simulations....

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Detalles Bibliográficos
Autores principales: Sinn, Stephan, Spuling, Eduard, Bräse, Stefan, Biedermann, Frank
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Royal Society of Chemistry 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6628674/
https://www.ncbi.nlm.nih.gov/pubmed/31367309
http://dx.doi.org/10.1039/c9sc00705a