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Rational design and implementation of a cucurbit[8]uril-based indicator-displacement assay for application in blood serum
In this study, we report the first supramolecular indicator-displacement assay (IDA) based on cucurbit[n]uril (CBn) hosts that is operational in blood serum. Rational design principles for host–guest chemosensing in competitively binding media were derived through detailed mathematical simulations....
Autores principales: | Sinn, Stephan, Spuling, Eduard, Bräse, Stefan, Biedermann, Frank |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Royal Society of Chemistry
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6628674/ https://www.ncbi.nlm.nih.gov/pubmed/31367309 http://dx.doi.org/10.1039/c9sc00705a |
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