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A heuristic derived from analysis of the ion channel structural proteome permits the rapid identification of hydrophobic gates
Ion channel proteins control ionic flux across biological membranes through conformational changes in their transmembrane pores. An exponentially increasing number of channel structures captured in different conformational states are now being determined; however, these newly resolved structures are...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
National Academy of Sciences
2019
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6628796/ https://www.ncbi.nlm.nih.gov/pubmed/31235590 http://dx.doi.org/10.1073/pnas.1902702116 |