Cargando…

Concurrent Exposure of Neutralizing and Non-neutralizing Epitopes on a Single HIV-1 Envelope Structure

The trimeric envelope spikes on the HIV-1 virus surface initiate infection and comprise key targets for antiviral humoral responses. Circulating virions variably present intact envelope spikes, which react with neutralizing antibodies; and altered envelope structures, which bind non-neutralizing ant...

Descripción completa

Detalles Bibliográficos
Autores principales: Ray, Krishanu, Mengistu, Meron, Orlandi, Chiara, Pazgier, Marzena, Lewis, George K., DeVico, Anthony L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6628914/
https://www.ncbi.nlm.nih.gov/pubmed/31338095
http://dx.doi.org/10.3389/fimmu.2019.01512