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Concurrent Exposure of Neutralizing and Non-neutralizing Epitopes on a Single HIV-1 Envelope Structure
The trimeric envelope spikes on the HIV-1 virus surface initiate infection and comprise key targets for antiviral humoral responses. Circulating virions variably present intact envelope spikes, which react with neutralizing antibodies; and altered envelope structures, which bind non-neutralizing ant...
Autores principales: | Ray, Krishanu, Mengistu, Meron, Orlandi, Chiara, Pazgier, Marzena, Lewis, George K., DeVico, Anthony L. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6628914/ https://www.ncbi.nlm.nih.gov/pubmed/31338095 http://dx.doi.org/10.3389/fimmu.2019.01512 |
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