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Efficacy of combinations of colistin with other antimicrobials involves membrane fluidity and efflux machinery

OBJECTIVE: Despite its use was abandoned several decades ago, the polycationic peptide colistin has become the last hope to treat severe infections caused by multidrug-resistant Gram-negative bacteria. Thus, the development of colistin resistance may seriously compromise the efficacy of treatment. M...

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Detalles Bibliográficos
Autores principales: Armengol, E, Domenech, O, Fusté, E, Pérez-Guillén, I, Borrell, JH, Sierra, JM, Vinas, M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6628955/
https://www.ncbi.nlm.nih.gov/pubmed/31372011
http://dx.doi.org/10.2147/IDR.S207844