Grape seed proanthocyanidins ameliorate neuronal oxidative damage by inhibiting GSK-3β-dependent mitochondrial permeability transition pore opening in an experimental model of sporadic Alzheimer’s disease

Mitochondria-associated oxidative stress plays a crucial role in Alzheimer’s disease (AD). Grape seed proanthocyanidins (GSPs) have been reported to prevent oxidative stress. In this study, we investigated the underlying mechanisms of GSPs in protecting neurons against oxidative injury in an experim...

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Detalles Bibliográficos
Autores principales: Sun, Qinru, Jia, Ning, Li, Xin, Yang, Jie, Chen, Guomin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals 2019
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6628984/
https://www.ncbi.nlm.nih.gov/pubmed/31232699
http://dx.doi.org/10.18632/aging.102041

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6628984/
https://www.ncbi.nlm.nih.gov/pubmed/31232699
http://dx.doi.org/10.18632/aging.102041

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