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Mitofusin 2 plays a role in oocyte and follicle development, and is required to maintain ovarian follicular reserve during reproductive aging

Mitochondria change their shape through fusion and fission in order to adapt to their metabolic milieu. Mitofusin-2 (MFN2) is a key regulatory protein in this process, mediating mitochondrial fusion and interaction with endoplasmic reticulum. Targeted deletion of Mfn2 in oocytes resulted in mitochon...

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Detalles Bibliográficos
Autores principales: Zhang, Man, Bener, Muhammed Burak, Jiang, Zongliang, Wang, Tianren, Esencan, Ecem, Scott, Richard, Horvath, Tamas, Seli, Emre
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6628992/
https://www.ncbi.nlm.nih.gov/pubmed/31204316
http://dx.doi.org/10.18632/aging.102024