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Anti-aging interventions affect lifespan variability in sex, strain, diet and drug dependent fashion

Decreased forkhead box O1 (FoxO1) activity induces hyperlipidemia and increased PPARγ, leading to hyperlipidemia in association with endoplasmic reticulum (ER) stress. In the liver, aging and comorbidities such as hyperlipidemia and diabetes significantly influence a wide variety of steatosis, but t...

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Detalles Bibliográficos
Autores principales: Bartke, Andrzej, Evans, Tracy R., Musters, C.J.M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6628994/
https://www.ncbi.nlm.nih.gov/pubmed/31235676
http://dx.doi.org/10.18632/aging.102037