Intestinal stem cells acquire premature senescence and senescence associated secretory phenotype concurrent with persistent DNA damage after heavy ion radiation in mice

Heavy ion radiation, prevalent in outer space and relevant for radiotherapy, is densely ionizing and poses risk to stem cells that are key to intestinal homeostasis. Currently, the molecular spectrum of heavy ion radiation-induced perturbations in intestinal stem cells (ISCs), that could trigger int...

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Detalles Bibliográficos
Autores principales: Kumar, Santosh, Suman, Shubhankar, Fornace, Albert J, Datta, Kamal
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals 2019
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6629005/
https://www.ncbi.nlm.nih.gov/pubmed/31239406
http://dx.doi.org/10.18632/aging.102043

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6629005/
https://www.ncbi.nlm.nih.gov/pubmed/31239406
http://dx.doi.org/10.18632/aging.102043

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