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The VAMP-associated protein VAPB is required for cardiac and neuronal pacemaker channel function

Hyperpolarization-activated cyclic nucleotide–gated (HCN) channels encode neuronal and cardiac pacemaker currents. The composition of pacemaker channel complexes in different tissues is poorly understood, and the presence of additional HCN modulating subunits was speculated. Here we show that vesicl...

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Detalles Bibliográficos
Autores principales: Silbernagel, Nicole, Walecki, Magdalena, Schäfer, Martin K.-H., Kessler, Mirjam, Zobeiri, Mehrnoush, Rinné, Susanne, Kiper, Aytug K., Komadowski, Marlene A., Vowinkel, Kirsty S., Wemhöner, Konstantin, Fortmüller, Lisa, Schewe, Marcus, Dolga, Amalia M., Scekic-Zahirovic, Jelena, Matschke, Lina A., Culmsee, Carsten, Baukrowitz, Thomas, Monassier, Laurent, Ullrich, Nina D., Dupuis, Luc, Just, Steffen, Budde, Thomas, Fabritz, Larissa, Decher, Niels
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Federation of American Societies for Experimental Biology 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6629115/
https://www.ncbi.nlm.nih.gov/pubmed/29879376
http://dx.doi.org/10.1096/fj.201800246R