Targeted genetic screening in mice through haploid embryonic stem cells identifies critical genes in bone development

Mutagenic screening is powerful for identifying key genes involved in developmental processes. However, such screens are successful only in lower organisms. Here, we develop a targeted genetic screening approach in mice through combining androgenetic haploid embryonic stem cells (AG-haESCs) and clus...

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Detalles Bibliográficos
Autores principales: Bai, Meizhu, Han, Yujiao, Wu, Yuxuan, Liao, Jiaoyang, Li, Lin, Wang, Lijun, Li, Qing, Xing, Wenhui, Chen, Luonan, Zou, Weiguo, Li, Jinsong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2019
Materias:
Methods and Resources
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6629148/
https://www.ncbi.nlm.nih.gov/pubmed/31265461
http://dx.doi.org/10.1371/journal.pbio.3000350

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6629148/
https://www.ncbi.nlm.nih.gov/pubmed/31265461
http://dx.doi.org/10.1371/journal.pbio.3000350

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