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Inflammatory arthritis disrupts gut resolution mechanisms, promoting barrier breakdown by Porphyromonas gingivalis

Rheumatoid arthritis is linked with altered host immune responses and severe joint destruction. Recent evidence suggests that loss of gut homeostasis and barrier breach by pathobionts, including Porphyromonas gingivalis, may influence disease severity. The mechanism(s) leading to altered gut homeost...

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Detalles Bibliográficos
Autores principales: Flak, Magdalena B., Colas, Romain A., Muñoz-Atienza, Estefanía, Curtis, Michael A., Dalli, Jesmond, Pitzalis, Costantino
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Clinical Investigation 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6629160/
https://www.ncbi.nlm.nih.gov/pubmed/31292292
http://dx.doi.org/10.1172/jci.insight.125191