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DL-3-n-butylphthalide protects the blood-brain barrier against ischemia/hypoxia injury via upregulation of tight junction proteins

BACKGROUND: The increased permeability of the blood-brain barrier (BBB) induced by ischemia/hypoxia is generally correlated with alteration of tight junctions (TJs). DL-3-n-butylphthalide (NBP) has been shown to exert neuroprotective effects after ischemic injury. However, few studies have assessed...

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Detalles Bibliográficos
Autores principales: Ye, Zhan-Ying, Xing, Han-Ying, Wang, Bei, Liu, Min, Lv, Pei-Yuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wolters Kluwer Health 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6629356/
https://www.ncbi.nlm.nih.gov/pubmed/30939485
http://dx.doi.org/10.1097/CM9.0000000000000232