Cargando…

DL-3-n-butylphthalide protects the blood-brain barrier against ischemia/hypoxia injury via upregulation of tight junction proteins

BACKGROUND: The increased permeability of the blood-brain barrier (BBB) induced by ischemia/hypoxia is generally correlated with alteration of tight junctions (TJs). DL-3-n-butylphthalide (NBP) has been shown to exert neuroprotective effects after ischemic injury. However, few studies have assessed...

Descripción completa

Detalles Bibliográficos
Autores principales:	Ye, Zhan-Ying, Xing, Han-Ying, Wang, Bei, Liu, Min, Lv, Pei-Yuan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Wolters Kluwer Health 2019
Materias:	Original Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6629356/ https://www.ncbi.nlm.nih.gov/pubmed/30939485 http://dx.doi.org/10.1097/CM9.0000000000000232

Ejemplares similares

Dl‐3‐N‐butylphthalide promotes angiogenesis and upregulates sonic hedgehog expression after cerebral ischemia in rats
por: Zhou, Pan‐Ting, et al.
Publicado: (2019)

Inhibiting of GRASP65 Phosphorylation by DL-3-N-Butylphthalide Protects against Cerebral Ischemia-Reperfusion Injury via ERK Signaling
por: Zhu, Bei-lei, et al.
Publicado: (2018)

Protective Effect of Dl-3n-butylphthalide on Learning and Memory Impairment Induced by Chronic Intermittent Hypoxia-Hypercapnia Exposure
por: Min, Jing-jing, et al.
Publicado: (2014)

Protective effects of dl-3n-butylphthalide against diffuse brain injury
por: Zhao, Yaning, et al.
Publicado: (2013)

Effects of Dl-3-n-butylphthalide on Cerebral Ischemia Infarction in Rat Model by Mass Spectrometry Imaging
por: Liu, Run-Zhe, et al.
Publicado: (2017)

Effect of Dl-3-n-butylphthalide on mitochondrial Cox7c in models of cerebral ischemia/reperfusion injury
por: Jia, Jingjing, et al.
Publicado: (2023)

Hypoxia inducible factor-1alpha mediates protection of DL-3-n-butylphthalide in brain microvascular endothelial cells against oxygen glucose deprivation-induced injury☆
por: Yang, Weihong, et al.
Publicado: (2012)

Dl-3-n-butylphthalide regulates cholinergic dysfunction in chronic cerebral hypoperfusion rats
por: Sun, Yanan, et al.
Publicado: (2020)

DL-3-n-butylphthalide improved physical and learning and memory performance of rodents exposed to acute and chronic hypobaric hypoxia
por: Xu, Gang, et al.
Publicado: (2021)

Effects of Dl-3-n-butylphthalide on cognitive functions and blood–brain barrier in chronic cerebral hypoperfusion rats
por: Ma, Yang, et al.
Publicado: (2023)

Dl-3-n-Butylphthalide Exerts Dopaminergic Neuroprotection Through Inhibition of Neuroinflammation
por: Chen, Yajing, et al.
Publicado: (2019)

DL-3n-Butylphthalide Improves Blood–Brain Barrier Integrity in Rat After Middle Cerebral Artery Occlusion
por: Mamtilahun, Muyassar, et al.
Publicado: (2021)

Correction to: Effects of Dl-3‑n‑butylphthalide on cognitive functions and blood–brain barrier in chronic cerebral hypoperfusion rats
por: Ma, Yang, et al.
Publicado: (2023)

Vascular protection and regenerative effects of intranasal DL-3-N-butylphthalide treatment after ischaemic stroke in mice
por: Qu, Mengyao, et al.
Publicado: (2020)

Optimal DL-Methionyl-DL-Methionine Supplementation Improved Intestinal Physical Barrier Function by Changing Antioxidant Capacity, Apoptosis and Tight Junction Proteins in the Intestine of Juvenile Grass Carp (Ctenopharyngodon idella)
por: Wu, Pei, et al.
Publicado: (2022)

Dl-3-n-butylphthalide Reduces Neurovascular Inflammation and Ischemic Brain Injury in Mice
por: Yang, Chun-Sheng, et al.
Publicado: (2019)

Corrigendum: Dl-3-n-Butylphthalide Exerts Dopaminergic Neuroprotection Through Inhibition of Neuroinflammation
por: Chen, Yajing, et al.
Publicado: (2021)

Dl-NBP (Dl-3-N-Butylphthalide) Treatment Promotes Neurological Functional Recovery Accompanied by the Upregulation of White Matter Integrity and HIF-1α/VEGF/Notch/Dll4 Expression
por: Wang, Yanping, et al.
Publicado: (2020)

O-GlcNAcylation Inhibition Upregulates Connexin43 Expression in the Endothelium to Protect the Tight Junction Barrier in Diabetic Retinopathy
por: Liu, Guodong, et al.
Publicado: (2023)

Dl-3-n-Butylphthalide Ameliorates Diabetic Nephropathy by Ameliorating Excessive Fibrosis and Podocyte Apoptosis
por: Xu, Jingyu, et al.
Publicado: (2021)

Breaking through the tight junction barrier
Publicado: (1993)

DL-3-n-butylphthalide delays the onset and progression of diabetic cataract by inhibiting oxidative stress in rat diabetic model
por: Wang, Fuxu, et al.
Publicado: (2016)

Neuroprotective effect of Dl-3-n-butylphthalide against ischemia–reperfusion injury is mediated by ferroptosis regulation via the SLC7A11/GSH/GPX4 pathway and the attenuation of blood–brain barrier disruption
por: Xu, Shuangli, et al.
Publicado: (2023)

Dl-3-n-butylphthalide exerts neuroprotective effects by modulating hypoxia-inducible factor 1-alpha ubiquitination to attenuate oxidative stress-induced apoptosis
por: Li, Shuai, et al.
Publicado: (2023)

DL-3-n-butylphthalide for acute ischemic stroke: An updated systematic review and meta-analysis of randomized controlled trials
por: Wang, Huan, et al.
Publicado: (2022)

Dl-3-n-Butylphthalide promotes neovascularization and neurological recovery in a rat model of intracerebral hemorrhage
por: Tu, Ewen, et al.
Publicado: (2020)

DL-3-n-butylphthalide Increases Collateriogenesis and Functional Recovery after Focal Ischemic Stroke in Mice
por: Wei, Zheng Zachory, et al.
Publicado: (2021)

Tight junctions and the modulation of barrier function in disease
por: Förster, Carola
Publicado: (2008)

Tight Junctions of the Outer Blood Retina Barrier
por: Naylor, Aisling, et al.
Publicado: (2019)

Dl-3-n-butylphthalide prevents the disruption of blood-spinal cord barrier via inhibiting endoplasmic reticulum stress following spinal cord injury
por: Zheng, Binbin, et al.
Publicado: (2017)

Dl‐3n‐butylphthalide improves traumatic brain injury recovery via inhibiting autophagy‐induced blood‐brain barrier disruption and cell apoptosis
por: Wu, Fangfang, et al.
Publicado: (2019)

Interleukin-34 Restores Blood–Brain Barrier Integrity by Upregulating Tight Junction Proteins in Endothelial Cells
por: Jin, Shijie, et al.
Publicado: (2014)

Hypoxia/Aglycemia-Induced Endothelial Barrier Dysfunction and Tight Junction Protein Downregulation Can Be Ameliorated by Citicoline
por: Ma, Xiaotang, et al.
Publicado: (2013)

The efficacy and safety of Dl-3n-butylphthalide on progressive cerebral infarction: A randomized controlled STROBE study
por: Zhang, Chenhao, et al.
Publicado: (2017)

Dl-3-n-Butylphthalide Treatment Enhances Hemodynamics and Ameliorates Memory Deficits in Rats with Chronic Cerebral Hypoperfusion
por: Xiong, Zhilin, et al.
Publicado: (2017)

Dl-3-n-butylphthalide inhibits neuroinflammation by stimulating foxp3 and Ki-67 in an ischemic stroke model
por: Liu, Xi, et al.
Publicado: (2021)

Dl-3-n-Butylphthalide Reduces Cognitive Deficits and Alleviates Neuropathology in P301S Tau Transgenic Mice
por: Chang, Yanmin, et al.
Publicado: (2021)

DL-3-n-butylphthalide alleviates motor disturbance by suppressing ferroptosis in a rat model of Parkinson’s disease
por: Hu, Chun-Bo, et al.
Publicado: (2022)

DL-3-n-butylphthalide (NBP) alleviates poststroke cognitive impairment (PSCI) by suppressing neuroinflammation and oxidative stress
por: Zhang, Hui, et al.
Publicado: (2023)

Long-Term DL-3-n-Butylphthalide Treatment Alleviates Cognitive Impairment Correlate With Improving Synaptic Plasticity in SAMP8 Mice
por: Lv, Chaonan, et al.
Publicado: (2018)

Cannot write session to /tmp/vufind_sessions/sess_4ht7e4qmtm0v09dt62ed1b2tqj