Deletion of translin (Tsn) induces robust adiposity and hepatic steatosis without impairing glucose tolerance

OBJECTIVE: Translin knockout (KO) mice display robust adiposity. Recent studies indicate that translin and its partner protein, trax, regulate the microRNA and ATM kinase signaling pathways, both of which have been implicated in regulating metabolism. In the course of characterizing the metabolic pr...

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Detalles Bibliográficos
Autores principales: Shah, Aparna P., Johnson, Miranda D., Fu, Xiuping, Boersma, Gretha J., Shah, Madhura, Wolfgang, Michael J., Tamashiro, Kellie L., Baraban, Jay M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6629527/
https://www.ncbi.nlm.nih.gov/pubmed/30647452
http://dx.doi.org/10.1038/s41366-018-0315-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6629527/
https://www.ncbi.nlm.nih.gov/pubmed/30647452
http://dx.doi.org/10.1038/s41366-018-0315-7

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