DNA translocation mechanism of the MCM complex and implications for replication initiation

The DNA translocation activity of the minichromosome maintenance (MCM) complex powers DNA strand separation of the replication forks of eukaryotes and archaea. Here we illustrate an atomic level mechanism for this activity with a crystal structure of an archaeal MCM hexamer bound to single-stranded...

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Detalles Bibliográficos
Autores principales: Meagher, Martin, Epling, Leslie B., Enemark, Eric J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6629641/
https://www.ncbi.nlm.nih.gov/pubmed/31308367
http://dx.doi.org/10.1038/s41467-019-11074-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6629641/
https://www.ncbi.nlm.nih.gov/pubmed/31308367
http://dx.doi.org/10.1038/s41467-019-11074-3

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