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Detection of cell-type-specific risk-CpG sites in epigenome-wide association studies

In epigenome-wide association studies, the measured signals for each sample are a mixture of methylation profiles from different cell types. Current approaches to the association detection claim whether a cytosine-phosphate-guanine (CpG) site is associated with the phenotype or not at aggregate leve...

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Detalles Bibliográficos
Autores principales: Luo, Xiangyu, Yang, Can, Wei, Yingying
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6629651/
https://www.ncbi.nlm.nih.gov/pubmed/31308366
http://dx.doi.org/10.1038/s41467-019-10864-z