Loss of Cubilin, the intrinsic factor-vitamin B12 receptor, impairs visceral endoderm endocytosis and endodermal patterning in the mouse

The visceral endoderm is a polarized epithelial monolayer necessary for early embryonic development in rodents. A key feature of this epithelium is an active endocytosis and degradation of maternal nutrients, in addition to being the source of various signaling molecules or inhibitors required for t...

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Detalles Bibliográficos
Autores principales: Perea-Gomez, Aitana, Cases, Olivier, Lelièvre, Vincent, Pulina, Maria V., Collignon, Jérôme, Hadjantonakis, Anna-Katerina, Kozyraki, Renata
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6629654/
https://www.ncbi.nlm.nih.gov/pubmed/31308417
http://dx.doi.org/10.1038/s41598-019-46559-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6629654/
https://www.ncbi.nlm.nih.gov/pubmed/31308417
http://dx.doi.org/10.1038/s41598-019-46559-0

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