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Intrabody-based FRET probe to visualize endogenous histone acetylation

Post-translational histone modifications are major regulators of gene expression. However, conventional immunoassays do not provide sufficient information regarding their spatial and temporal dynamic changes. Fluorescence/Förster resonance energy transfer (FRET)-based probes are capable of monitorin...

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Detalles Bibliográficos
Autores principales: Chung, Chan-I, Sato, Yuko, Ohmuro-Matsuyama, Yuki, Machida, Shinichi, Kurumizaka, Hitoshi, Kimura, Hiroshi, Ueda, Hiroshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6629662/
https://www.ncbi.nlm.nih.gov/pubmed/31308423
http://dx.doi.org/10.1038/s41598-019-46573-2