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Structural visualization of key steps in nucleosome reorganization by human FACT

Facilitates chromatin transcription (FACT) is a histone chaperone, which accomplishes both nucleosome assembly and disassembly. Our combined cryo-electron microscopy (EM) and native mass spectrometry (MS) studies revealed novel key steps of nucleosome reorganization conducted by a Mid domain and its...

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Detalles Bibliográficos
Autores principales: Mayanagi, Kouta, Saikusa, Kazumi, Miyazaki, Naoyuki, Akashi, Satoko, Iwasaki, Kenji, Nishimura, Yoshifumi, Morikawa, Kosuke, Tsunaka, Yasuo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6629675/
https://www.ncbi.nlm.nih.gov/pubmed/31308435
http://dx.doi.org/10.1038/s41598-019-46617-7