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Evaluating BRCA mutation risk predictive models in a Chinese cohort in Taiwan

Accurate estimation of carrier probabilities of cancer susceptibility gene mutations is an important part of pre-test genetic counselling. Many predictive models are available but their applicability in the Asian population is uncertain. We evaluated the performance of five BRCA mutation risk predic...

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Detalles Bibliográficos
Autores principales: Hung, Fei-Hung, Wang, Yong Alison, Jian, Jhih-Wei, Peng, Hung-Pin, Hsieh, Ling-Ling, Hung, Chen-Fang, Yang, Max M., Yang, An-Suei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6629692/
https://www.ncbi.nlm.nih.gov/pubmed/31308460
http://dx.doi.org/10.1038/s41598-019-46707-6