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Nicotinamide Augments the Anti-Inflammatory Properties of Resveratrol through PARP1 Activation

Resveratrol (RSV) and nicotinamide (NAM) have garnered considerable attention due to their anti-inflammatory and anti-aging properties. NAM is a transient inhibitor of class III histone deacetylase SIRTs (silent mating type information regulation 2 homologs) and SIRT1 is an inhibitor of poly-ADP-rib...

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Detalles Bibliográficos
Autores principales: Yanez, Maria, Jhanji, Megha, Murphy, Kendall, Gower, R. Michael, Sajish, Mathew, Jabbarzadeh, Ehsan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6629694/
https://www.ncbi.nlm.nih.gov/pubmed/31308445
http://dx.doi.org/10.1038/s41598-019-46678-8