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Acute and chronic hypoxia differentially predispose lungs for metastases

Oscillations in oxygen levels affect malignant cell growth, survival, and metastasis, but also somatic cell behaviour. In this work, we studied the effect of the differential expression of the two primary hypoxia inducible transcription factor isoforms, HIF-1α and HIF-2α, and pulmonary hypoxia to in...

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Detalles Bibliográficos
Autores principales: Reiterer, Moritz, Colaço, Renato, Emrouznejad, Pardis, Jensen, Anders, Rundqvist, Helene, Johnson, Randall S., Branco, Cristina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6629695/
https://www.ncbi.nlm.nih.gov/pubmed/31308473
http://dx.doi.org/10.1038/s41598-019-46763-y