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The Kindlin2-p53-SerpinB2 signaling axis is required for cellular senescence in breast cancer
In cancer, cellular senescence is a complex process that leads to inhibition of proliferation of cells that may develop a neoplastic phenotype. A plethora of signaling pathways, when dysregulated, have been shown to elicit a senescence response. Two well-known tumor suppressor pathways, controlled b...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6629707/ https://www.ncbi.nlm.nih.gov/pubmed/31308359 http://dx.doi.org/10.1038/s41419-019-1774-z |