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Domain swapping of complementarity-determining region in nanobodies produced by Pichia pastoris

Easy preparation of chimeric nanobodies with various scaffolds is important for customizing abilities of nanobodies toward practical utilization. To accomplish high-throughput production of various nanobodies, utilization of microbes is an attractive option. In the present study, various chimeric na...

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Detalles Bibliográficos
Autores principales: Miura, Natsuko, Miyamoto, Kana, Ohtani, Yuta, Yaginuma, Kenshi, Aburaya, Shunsuke, Kitagawa, Yoshinori, Aoki, Wataru, Ueda, Mitsuyoshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6629726/
https://www.ncbi.nlm.nih.gov/pubmed/31309388
http://dx.doi.org/10.1186/s13568-019-0833-2