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Domain swapping of complementarity-determining region in nanobodies produced by Pichia pastoris
Easy preparation of chimeric nanobodies with various scaffolds is important for customizing abilities of nanobodies toward practical utilization. To accomplish high-throughput production of various nanobodies, utilization of microbes is an attractive option. In the present study, various chimeric na...
Autores principales: | Miura, Natsuko, Miyamoto, Kana, Ohtani, Yuta, Yaginuma, Kenshi, Aburaya, Shunsuke, Kitagawa, Yoshinori, Aoki, Wataru, Ueda, Mitsuyoshi |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer Berlin Heidelberg
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6629726/ https://www.ncbi.nlm.nih.gov/pubmed/31309388 http://dx.doi.org/10.1186/s13568-019-0833-2 |
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