Targeting autophagy potentiates the anti-tumor effect of PARP inhibitor in pediatric chronic myeloid leukemia

Due to its potent cytotoxicity in BRCA-mutated tumors, synthetic lethality elicited by poly (ADP-ribose) polymerase (PARP) inhibitor gives renewed enthusiasm to researching and developing anti-cancer therapies. Chronic myeloid leukemia (CML) is a type of cancers that starts in certain blood-forming...

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Detalles Bibliográficos
Autores principales: Liu, Yuanyuan, Song, Hong, Song, Huanqing, Feng, Xiaoxia, Zhou, Chuan, Huo, Zhifang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2019
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6629728/
https://www.ncbi.nlm.nih.gov/pubmed/31309361
http://dx.doi.org/10.1186/s13568-019-0836-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6629728/
https://www.ncbi.nlm.nih.gov/pubmed/31309361
http://dx.doi.org/10.1186/s13568-019-0836-z

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