Risk of Atrial Fibrillation in Patients with Congenital Heart Disease: Results of a Propensity Score-Matched, Nationwide Cohort Study

Aim: The objective was to compare the rate of atrial fibrillation (AF) onset in patients with congenital heart disease (CHD) compared to controls. Methods: Using a large number of samples extracted from nationwide cohort data in Taiwan, the authors used a propensity-matching procedure and multivaria...

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Autores principales: Hu, Wei-Syun, Lin, Cheng-Li
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Japan Atherosclerosis Society 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6629750/
https://www.ncbi.nlm.nih.gov/pubmed/31231081
http://dx.doi.org/10.5551/jat.48835
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author Hu, Wei-Syun
Lin, Cheng-Li
author_facet Hu, Wei-Syun
Lin, Cheng-Li
author_sort Hu, Wei-Syun
collection PubMed
description Aim: The objective was to compare the rate of atrial fibrillation (AF) onset in patients with congenital heart disease (CHD) compared to controls. Methods: Using a large number of samples extracted from nationwide cohort data in Taiwan, the authors used a propensity-matching procedure and multivariable Cox models to assess the risk of AF by CHD. Results: A cohort of 19,439 CHD patients and a propensity-matched cohort of 19,439 control patients were included in this study. The cumulative incidence of AF was significantly higher in the CHD cohort than in the non-CHD cohort (p<0.001). After controlling for confounding factors, the adjusted hazard ratio (aHR) of AF was 4.23 (95% confidence interval [CI] 3.31-5.41) in the CHD cohort, compared to the non-CHD cohort. Conclusion: A significant association between CHD and AF risk was found.
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spelling pubmed-66297502019-07-23 Risk of Atrial Fibrillation in Patients with Congenital Heart Disease: Results of a Propensity Score-Matched, Nationwide Cohort Study Hu, Wei-Syun Lin, Cheng-Li J Atheroscler Thromb Original Article Aim: The objective was to compare the rate of atrial fibrillation (AF) onset in patients with congenital heart disease (CHD) compared to controls. Methods: Using a large number of samples extracted from nationwide cohort data in Taiwan, the authors used a propensity-matching procedure and multivariable Cox models to assess the risk of AF by CHD. Results: A cohort of 19,439 CHD patients and a propensity-matched cohort of 19,439 control patients were included in this study. The cumulative incidence of AF was significantly higher in the CHD cohort than in the non-CHD cohort (p<0.001). After controlling for confounding factors, the adjusted hazard ratio (aHR) of AF was 4.23 (95% confidence interval [CI] 3.31-5.41) in the CHD cohort, compared to the non-CHD cohort. Conclusion: A significant association between CHD and AF risk was found. Japan Atherosclerosis Society 2019-07-01 /pmc/articles/PMC6629750/ /pubmed/31231081 http://dx.doi.org/10.5551/jat.48835 Text en 2019 Japan Atherosclerosis Society This article is distributed under the terms of the latest version of CC BY-NC-SA defined by the Creative Commons Attribution License.http://creativecommons.org/licenses/by-nc-sa/3.0/
spellingShingle Original Article
Hu, Wei-Syun
Lin, Cheng-Li
Risk of Atrial Fibrillation in Patients with Congenital Heart Disease: Results of a Propensity Score-Matched, Nationwide Cohort Study
title Risk of Atrial Fibrillation in Patients with Congenital Heart Disease: Results of a Propensity Score-Matched, Nationwide Cohort Study
title_full Risk of Atrial Fibrillation in Patients with Congenital Heart Disease: Results of a Propensity Score-Matched, Nationwide Cohort Study
title_fullStr Risk of Atrial Fibrillation in Patients with Congenital Heart Disease: Results of a Propensity Score-Matched, Nationwide Cohort Study
title_full_unstemmed Risk of Atrial Fibrillation in Patients with Congenital Heart Disease: Results of a Propensity Score-Matched, Nationwide Cohort Study
title_short Risk of Atrial Fibrillation in Patients with Congenital Heart Disease: Results of a Propensity Score-Matched, Nationwide Cohort Study
title_sort risk of atrial fibrillation in patients with congenital heart disease: results of a propensity score-matched, nationwide cohort study
topic Original Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6629750/
https://www.ncbi.nlm.nih.gov/pubmed/31231081
http://dx.doi.org/10.5551/jat.48835
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