The Landscape of SNCA Transcripts Across Synucleinopathies: New Insights From Long Reads Sequencing Analysis

Dysregulation of alpha-synuclein expression has been implicated in the pathogenesis of synucleinopathies, in particular Parkinson’s Disease (PD) and Dementia with Lewy bodies (DLB). Previous studies have shown that the alternatively spliced isoforms of the SNCA gene are differentially expressed in d...

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Detalles Bibliográficos
Autores principales: Tseng, Elizabeth, Rowell, William J., Glenn, Omolara-Chinue, Hon, Ting, Barrera, Julio, Kujawa, Steve, Chiba-Falek, Ornit
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Genetics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6629766/
https://www.ncbi.nlm.nih.gov/pubmed/31338105
http://dx.doi.org/10.3389/fgene.2019.00584

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6629766/
https://www.ncbi.nlm.nih.gov/pubmed/31338105
http://dx.doi.org/10.3389/fgene.2019.00584

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