Five-Feature Model for Developing the Classifier for Synergistic vs. Antagonistic Drug Combinations Built by XGBoost

Combinatorial drug therapy can improve the therapeutic effect and reduce the corresponding adverse events. In silico strategies to classify synergistic vs. antagonistic drug pairs is more efficient than experimental strategies. However, most of the developed methods have been applied only to cancer...

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Detalles Bibliográficos
Autores principales: Ji, Xiangjun, Tong, Weida, Liu, Zhichao, Shi, Tieliu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Genetics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6629777/
https://www.ncbi.nlm.nih.gov/pubmed/31338106
http://dx.doi.org/10.3389/fgene.2019.00600

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6629777/
https://www.ncbi.nlm.nih.gov/pubmed/31338106
http://dx.doi.org/10.3389/fgene.2019.00600

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