Simultaneous Semi-Mechanistic Population Pharmacokinetic Modeling Analysis of Enalapril and Enalaprilat Serum and Urine Concentrations From Child Appropriate Orodispersible Minitablets

Enalapril is recommended as the first line of therapy and is proven to improve survival rates for treatment of Pediatric Heart Failure; however, an approved drug and child appropriate dosage formulation is still absent. The present analysis was conducted to perform a detailed model informed populati...

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Detalles Bibliográficos
Autores principales: Faisal, Muhammad, Cawello, Willi, Burckhardt, Bjoern B., de Hoon, Jan, Laer, Stephanie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Pediatrics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6629781/
https://www.ncbi.nlm.nih.gov/pubmed/31338356
http://dx.doi.org/10.3389/fped.2019.00281

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6629781/
https://www.ncbi.nlm.nih.gov/pubmed/31338356
http://dx.doi.org/10.3389/fped.2019.00281

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