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Recent Advances in Understanding Mammalian Prion Structure: A Mini Review
Prions are lethal pathogens, which cause fatal neurodegenerative diseases in mammals. They are unique infectious agents and are composed of self-propagating multi-chain assemblies of misfolded host-encoded prion protein (PrP). Understanding prion structure is fundamental to understanding prion disea...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2019
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6629788/ https://www.ncbi.nlm.nih.gov/pubmed/31338021 http://dx.doi.org/10.3389/fnmol.2019.00169 |