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Recent Advances in Understanding Mammalian Prion Structure: A Mini Review

Prions are lethal pathogens, which cause fatal neurodegenerative diseases in mammals. They are unique infectious agents and are composed of self-propagating multi-chain assemblies of misfolded host-encoded prion protein (PrP). Understanding prion structure is fundamental to understanding prion disea...

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Detalles Bibliográficos
Autores principales: Terry, Cassandra, Wadsworth, Jonathan D. F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6629788/
https://www.ncbi.nlm.nih.gov/pubmed/31338021
http://dx.doi.org/10.3389/fnmol.2019.00169