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Distinct Conformations, Aggregation and Cellular Internalization of Different Tau Strains
The inter-cellular propagation of tau aggregates in several neurodegenerative diseases involves, in part, recurring cycles of extracellular tau uptake, initiation of endogenous tau aggregation, and extracellular release of at least part of this protein complex. However, human brain tau extracts from...
Autores principales: | Karikari, Thomas K., Nagel, David A., Grainger, Alastair, Clarke-Bland, Charlotte, Crowe, James, Hill, Eric J., Moffat, Kevin G. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6629824/ https://www.ncbi.nlm.nih.gov/pubmed/31338022 http://dx.doi.org/10.3389/fncel.2019.00296 |
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