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BK channel clustering is required for normal behavioral alcohol sensitivity in C. elegans

The large conductance, calcium- and voltage-activated potassium channel, known as the BK channel, is one of the central proteins that mediate alcohol intoxication and tolerance across species. Although ethanol targets BK channels through direct interaction, how ethanol-mediated BK channel activation...

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Detalles Bibliográficos
Autores principales: Oh, Kelly H., Kim, Hongkyun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6629859/
https://www.ncbi.nlm.nih.gov/pubmed/31308408
http://dx.doi.org/10.1038/s41598-019-46615-9