The Exaptation of HERV-H: Evolutionary Analyses Reveal the Genomic Features of Highly Transcribed Elements

HERV-H endogenous retroviruses are thought to be essential to stem cell identity in humans. We embrace several decades of HERV-H research in order to relate the transcription of HERV-H loci to their genomic structure. We find that highly transcribed HERV-H loci are younger, more fragmented, and less...

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Detalles Bibliográficos
Autores principales: Gemmell, Patrick, Hein, Jotun, Katzourakis, Aris
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6629862/
https://www.ncbi.nlm.nih.gov/pubmed/31338090
http://dx.doi.org/10.3389/fimmu.2019.01339

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6629862/
https://www.ncbi.nlm.nih.gov/pubmed/31338090
http://dx.doi.org/10.3389/fimmu.2019.01339

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