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Astrocytic Insulin-Like Growth Factor-1 Protects Neurons Against Excitotoxicity
BACKGROUND: Exogenous insulin like growth factor-1 (IGF-1) is known to be neuroprotective in animal models with brain insults, while it can also cause hyperexcitability in rodents. In this regard, the role of endogenous IGF-1 in brain responses to brain insults like excitotoxicity, a common patholog...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6629877/ https://www.ncbi.nlm.nih.gov/pubmed/31338023 http://dx.doi.org/10.3389/fncel.2019.00298 |