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Ruthenium Complexes Containing Heterocyclic Thioamidates Trigger Caspase-Mediated Apoptosis Through MAPK Signaling in Human Hepatocellular Carcinoma Cells

Herein, ruthenium complexes containing heterocyclic thioamidates [Ru(mmi)(bipy)(dppb)]PF(6) (1), [Ru(tzdt)(bipy)(dppb)]PF(6) (2), [Ru(dmp)(bipy)(dppb)]PF(6) (3) and [Ru(mpca)(bipy)(dppb)]PF(6) (4) were investigated for their cellular and molecular effects in cancer cell lines. Complexes 1 and 2 were...

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Detalles Bibliográficos
Autores principales: Neves, Sara P., de Carvalho, Nanashara C., da Silva, Monize M., Rodrigues, Ana Carolina B. C., Bomfim, Larissa M., Dias, Rosane B., Sales, Caroline B. S., Rocha, Clarissa A. Gurgel, Soares, Milena B. P., Batista, Alzir A., Bezerra, Daniel P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6629894/
https://www.ncbi.nlm.nih.gov/pubmed/31338323
http://dx.doi.org/10.3389/fonc.2019.00562