Histamine-Induced Conjunctivitis and Breakdown of Blood–Tear Barrier in Dogs: A Model for Ocular Pharmacology and Therapeutics

Conjunctival inflammation disturbs the blood–tear barrier and thus affects the tear film stability and composition. We aimed to develop a non-invasive and reliable method to induce conjunctivitis in dogs, a large animal model for translational work on ocular surface disease in humans. Six beagle dog...

Descripción completa

Detalles Bibliográficos
Autores principales: Sebbag, Lionel, Allbaugh, Rachel A., Weaver, Amanda, Seo, Yeon-Jung, Mochel, Jonathan P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6629934/
https://www.ncbi.nlm.nih.gov/pubmed/31354477
http://dx.doi.org/10.3389/fphar.2019.00752

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6629934/
https://www.ncbi.nlm.nih.gov/pubmed/31354477
http://dx.doi.org/10.3389/fphar.2019.00752

Ejemplares similares