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MicroRNA-222 promotes drug resistance to doxorubicin in breast cancer via regulation of miR-222/bim pathway

Resistance to doxorubicin (DOX) is the most common clinical problem in breast cancer therapy, and the underlying molecular mechanism remains to be investigated. MicroRNAs (miRNAs) exhibit important regulatory functions in various malignant tumors including breast cancer. The aim of the present study...

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Detalles Bibliográficos
Autores principales: Dai, Hong, Xu, Ling-yun, Qian, Qi, Zhu, Qiu-wei, Chen, Wei-xian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Portland Press Ltd. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6629945/
https://www.ncbi.nlm.nih.gov/pubmed/31273056
http://dx.doi.org/10.1042/BSR20190650