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Immunological evidence for in vivo production of novel advanced glycation end-products from 1,5-anhydro-D-fructose, a glycogen metabolite

The anhydrofructose pathway is an alternate pathway for glycogen degradation by α-1,4-glucan lyase. The sugar 1,5-anhydro-D-fructose (1,5-AF) acts as the central intermediate of this pathway, but its physiological role of in mammals is unclear. Glycation reactions forming advanced glycation end-prod...

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Detalles Bibliográficos
Autores principales: Sakasai-Sakai, Akiko, Takata, Takanobu, Suzuki, Hirokazu, Maruyama, Ikuro, Motomiya, Yoshihiro, Takeuchi, Masayoshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6629992/
https://www.ncbi.nlm.nih.gov/pubmed/31308400
http://dx.doi.org/10.1038/s41598-019-46333-2