Atomistic mechanisms underlying the activation of the G protein-coupled sweet receptor heterodimer by sugar alcohol recognition

The human T1R2-T1R3 sweet taste receptor (STR) plays an important role in recognizing various low-molecular-weight sweet-tasting sugars and proteins, resulting in the release of intracellular heterotrimeric G protein that in turn leads to the sweet taste perception. Xylitol and sorbitol, which are n...

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Detalles Bibliográficos
Autores principales: Mahalapbutr, Panupong, Darai, Nitchakan, Panman, Wanwisa, Opasmahakul, Aunchan, Kungwan, Nawee, Hannongbua, Supot, Rungrotmongkol, Thanyada
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6629994/
https://www.ncbi.nlm.nih.gov/pubmed/31308429
http://dx.doi.org/10.1038/s41598-019-46668-w

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6629994/
https://www.ncbi.nlm.nih.gov/pubmed/31308429
http://dx.doi.org/10.1038/s41598-019-46668-w

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