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Proteome Profiling of Exosomes Purified from a Small Amount of Human Serum: The Problem of Co-Purified Serum Components

Untargeted proteomics analysis of extracellular vesicles (EVs) isolated from human serum or plasma remains a technical challenge due to the contamination of these vesicles with lipoproteins and other abundant serum components. Here we aimed to test a simple method of EV isolation from a small amount...

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Detalles Bibliográficos
Autores principales: Smolarz, Mateusz, Pietrowska, Monika, Matysiak, Natalia, Mielańczyk, Łukasz, Widłak, Piotr
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6630217/
https://www.ncbi.nlm.nih.gov/pubmed/31035355
http://dx.doi.org/10.3390/proteomes7020018