Optimization of Innovative Three-Dimensionally-Structured Hybrid Vesicles to Improve the Cutaneous Delivery of Clotrimazole for the Treatment of Topical Candidiasis

New three-dimensionally-structured hybrid phospholipid vesicles, able to load clotrimazole in a high amount (10 mg/mL), were obtained for the first time in this work by significantly reducing the amount of water (≤10%), which was replaced with a mixture of glycerol and ethanol (≈90%). A pre-formulat...

Descripción completa

Detalles Bibliográficos
Autores principales: Manca, Maria Letizia, Usach, Iris, Peris, José Esteban, Ibba, Antonella, Orrù, Germano, Valenti, Donatella, Escribano-Ferrer, Elvira, Gomez-Fernandez, Juan Carmelo, Aranda, Francisco José, Fadda, Anna Maria, Manconi, Maria
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6630241/
https://www.ncbi.nlm.nih.gov/pubmed/31174342
http://dx.doi.org/10.3390/pharmaceutics11060263

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6630241/
https://www.ncbi.nlm.nih.gov/pubmed/31174342
http://dx.doi.org/10.3390/pharmaceutics11060263

Ejemplares similares