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Detection of somatic mutations in ctDNA derived from adenocarcinoma patients – EGFR tyrosine kinase inhibitor monitoring preliminary study

AIM OF THE STUDY: The main purpose of this study was to assess detection of mutations in the epidermal growth factor receptor (EGFR) gene in circulating tumor DNA (ctDNA) as a tool for EGFR tyrosine kinase inhibitor (TKI) monitoring therapy. MATERIAL AND METHODS: The study was conducted using 20 sam...

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Detalles Bibliográficos
Autores principales: Lewandowska, Marzena Anna, Nalejska, Ewelina, Żołna, Łukasz, Chrząstek, Aleksandra, Żurawski, Bogdan, Wiśniewska, Magdalena, Las-Jankowska, Manuela, Roszkowski, Krzysztof, Kowalewski, Janusz
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Termedia Publishing House 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6630386/
https://www.ncbi.nlm.nih.gov/pubmed/31316290
http://dx.doi.org/10.5114/wo.2019.85879