Reporter Cell Assessment of TLR4-Induced NF-κB Responses to Cell-Free Hemoglobin and the Influence of Biliverdin

Hemoglobin (Hb) released during red blood cell lysis can initiate TLR4-dependent signaling and trigger NF-κB activation in surrounding cells. Observations of chronic bleeding in various cancers leads us to hypothesize that Hb and Hb degradation products released from lysed RBC near cancer nests migh...

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Detalles Bibliográficos
Autores principales: Sharma, Jill, Boyd, Taylor, Alvarado, Claudia, Gunn, Edwin, Adams, Jaimie, Ness, Traci, Dunwoody, Robert, Lamb, John, House, Brittany, Knapp, James, Garner, Ronald
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6630411/
https://www.ncbi.nlm.nih.gov/pubmed/31163699
http://dx.doi.org/10.3390/biomedicines7020041

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6630411/
https://www.ncbi.nlm.nih.gov/pubmed/31163699
http://dx.doi.org/10.3390/biomedicines7020041

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