Optimization of Polyarginine-Conjugated PEG Lipid Grafted Proliposome Formulation for Enhanced Cellular Association of a Protein Drug

The purpose of this study was to develop an oral proliposomal powder of protein using poly-l-arginine-conjugated 1,2-distearoyl-sn-glycero-3-phosphoethanolamine-poly(ethylene glycol) (DSPE-PEG) (PLD) for enhancing cellular association upon reconstitution and to compare its effects with a non-grafted...

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Detalles Bibliográficos
Autores principales: Tunsirikongkon, Amolnat, Pyo, Yong-Chul, Kim, Dong-Hyun, Lee, Sang-Eun, Park, Jeong-Sook
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6630419/
https://www.ncbi.nlm.nih.gov/pubmed/31212607
http://dx.doi.org/10.3390/pharmaceutics11060272

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6630419/
https://www.ncbi.nlm.nih.gov/pubmed/31212607
http://dx.doi.org/10.3390/pharmaceutics11060272

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