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β-Cyclodextrin as a Functional Excipient Used for Enhancing the Diminazene Aceturate Bioavailability

In this study, we proposed formulations of diminazene aceturate (DA) designed to improve its bioavailability and to maximize the therapeutic index in animals by overcoming the rapid degradation under the acidic pH of the stomach. An important consequence is the fact that its amount in the bloodstrea...

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Detalles Bibliográficos
Autores principales: Marangoci, Narcisa, Timpu, Daniel, Corciova, Andreia, Mircea, Cornelia, Petrovici, Anca-Roxana, Nicolescu, Alina, Ursu, Elena-Laura, Nastasa, Valentin, Bostanaru, Andra-Cristina, Mares, Mihai, Pertea, Mihaela, Pinteala, Mariana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6630424/
https://www.ncbi.nlm.nih.gov/pubmed/31234525
http://dx.doi.org/10.3390/pharmaceutics11060295